Cytochrome P450 2A6 Chr. Chromosome 19 (human)[1] Available structuresPDBList of PDB id codes Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes4RUI, 1Z10, 1Z11, 2FDU, 2FDV, 2FDW, 2FDY, 3EBS, 3T3Q, 3T3R, 4EJJ List of PDB id codes List of PDB id codes4RUI, 1Z10, 1Z11, 2FDU, 2FDV, 2FDW, 2FDY, 3EBS, 3T3Q, 3T3R, 4EJJ UniProt P11509 Location (UCSC) Chr 19: 40.84 – 40.85 Mb PubMed search [2] RefSeq (protein) NP_000753 Aliases CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB, cytochrome P450 family 2 subfamily A member 6 RefSeq (mRNA) NM_000762 PDB Human UniProt search: PDBe RCSB Cellular component • organelle membrane• endoplasmic reticulum membrane• เยื่อหุ้ม• intracellular membrane-bounded organelle• ร่างแหเอนโดพลาซึม• cytoplasmic microtubule• ไซโทพลาซึม Gene ontologyMolecular functionCellular componentBiological process Gene ontologyMolecular function• iron ion binding• arachidonic acid epoxygenase activity• oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen• metal ion binding• monooxygenase activity• heme binding• oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen• enzyme binding• oxidoreductase activity• coumarin 7-hydroxylase activity• steroid hydroxylase activityCellular component• organelle membrane• endoplasmic reticulum membrane• เยื่อหุ้ม• intracellular membrane-bounded organelle• ร่างแหเอนโดพลาซึม• cytoplasmic microtubule• ไซโทพลาซึมBiological process• steroid metabolic process• exogenous drug catabolic process• epoxygenase P450 pathway• coumarin catabolic process• drug metabolic process• coumarin metabolic process• organic acid metabolic process• xenobiotic metabolic processSources:Amigo / QuickGO External IDs OMIM: 122720 HomoloGene: 85917 GeneCards: CYP2A6 End 40,850,447 bp[1] Ensembl ENSG00000255974 Molecular function • iron ion binding• arachidonic acid epoxygenase activity• oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen• metal ion binding• monooxygenase activity• heme binding• oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen• enzyme binding• oxidoreductase activity• coumarin 7-hydroxylase activity• steroid hydroxylase activity Species Human Biological process • steroid metabolic process• exogenous drug catabolic process• epoxygenase P450 pathway• coumarin catabolic process• drug metabolic process• coumarin metabolic process• organic acid metabolic process• xenobiotic metabolic process BandStart 19q13.2 Gene location (Human)Chr.BandStartEnd Gene location (Human)Chr.Chromosome 19 (human)[1]Band19q13.2Start40,843,541 bp[1]End40,850,447 bp[1] Entrez 1548
เมนูนำทาง Cytochrome P450 2A6 การกระจายและความผันแปร ดูเพิ่ม ตัวอย่างผังปฏิสัมพันธ์ อ้างอิง ลิแกนด์ของ CYP2A6
ใกล้เคียง Cytochrome P450 3A4 Cytochrome P450 2B6 Cytochrome P450 3A5 Cytochrome P450 2C9 Cytochrome P450 2A6 Cytochrome P450 2C8 Cytochrome P450 2A7 Cytochrome P450 2A13 Cytochrome P450 3A7 Cytochrome P450 3A43
